Оригинальные и переводные издания на русском языке, выпущенные в России в дореволюционный и советский период

Ovarian Cancer

Автор: Bartlett J. M. S.
Год выпуска: 2001
Издательство: Humana Press
Страниц: 817

Cancers are highly complex disease systems that require access to widely diverse laboratory techniques from a broad range of research disciplines, methods that are often beyond the knowledge of a single researcher. In Ovarian Cancer: Methods and Protocols, over one hundred well-respected scientists comprehensively review every aspect of the biology underlying ovarian cancer and present a detailed collection of easy-to-follow methods for illuminating this frequently fatal disease’s basic mechanisms. Here today’s investigators will find the broadest imaginable array of molecular biology techniques specially designed to determine not only tumor genetics, expression, and protein function, but also to elucidate the genetic mechanisms by which gene and immunotherapies may be perfected. The book’s highly experienced authors provide help in selecting the correct model system for each experimental approach, and offer extensive technical advice to facilitate the planning of individual experiments and ensure that researchers are using the optimal techniques for their research programs. Although structured primarily for ovarian cancer researchers, and using examples from that field, the techniques can be immediately applied to research in many other tumor types. Versatile and comprehensive, Ovarian Cancer Methods and Protocols constitutes a veritable treasury of well-proven expert methods that will help basic scientists and clinical researchers alike master the powerful technologies required for effective cancer research today.

Ovarian Cancer. Methods and Protocols

The Epidemiology of Ovarian Cancer
Familial Ovarian Cancer
The Molecular Pathogenesis of Ovarian Cancer
Alterations in Oncogenes, Tumor Suppressor Genes, and Growth Factors Associated with Epithelial Ovarian Cancers
Pathological Assessment of Ovarian Cancer
Tumor Markers in Screening for Ovarian Cancer
Primary Surgical Management of Ovarian Cancer
Recent Insights into Drug Resistance in Ovarian Cancer
Markers of Tumor Burden
Bioactive Interleukin-6 Levels in Serum and Ascites as a Prognostic Factor in Patients with Epithelial Ovarian
ELISA-Based Quantification of p105 (c-erbB-2, HER2/neu) in Serum of Ovarian Carcinoma
Enzyme Immunoassay of Urinary β-Core Fragment of Human Chorionic Gonadotropin as a Tumor Marker for Ovarian Cancer
Ovarian Cancer Models
Establishment of Ovarian Cancer Cell Lines
Subcloning of Ovarian Cancer Cell Lines
Culture and Characterization of Human Ovarian Surface Epithelium
MTT Growth Assays in Ovarian Cancer
In Vitro Invasion Assays
p53Transfectants in Ovarian Cancer
Estrogen-Responsive Ovarian Cancer Xenografts
The Use of Matrigel in the Establishment of Ovarian Carcinoma Cell Lines as Xenografts
Cytogenetics of Ovarian Cancer Technical Overview
Interphase Cytogenetics in Frozen Ovarian Tumor Tissue
Interphase Cytogenetics in Paraffin-Embedded Ovarian Tissue
Rapid Identification of Chromosomes Using Primed In Situ Labeling (PRINS)

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